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1

Efficient synthesis of 6-(hetero)arylthieno[3,2-b]pyridines by Suzuki–Miyaura coupling. Evaluation of growth inhibition on human tumor cell lines, SARs and effects on the cell cycle

Maria-João R.P. Queiroz, Ricardo C. Calhelha, Luís A. Vale-Silva, Eugénia Pinto, Raquel T. Lima, M. Helena Vasconcelos

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 602 KB

english, 2010

2

Antifungal Activity of Xanthones: Evaluation of their Effect on Ergosterol Biosynthesis by High-performance Liquid Chromatography

Eugénia Pinto, Carlos Afonso, Serafim Duarte, Luís Vale-Silva, Elisangela Costa, Emília Sousa, Madalena Pinto

Journal:

Chemical Biology & Drug Design

Year:

2011

Language:

english

File:

PDF, 332 KB

english, 2011

3

ChemInform Abstract: Synthesis of Novel 3-(Aryl)benzothieno[2,3-c]pyran-1-ones from Sonogashira Products and Intramolecular Cyclization: Antitumoral Activity Evaluation.

Maria-Joao R. P. Queiroz, Ricardo C. Calhelha, Luis A. Vale-Silva, Eugenia Pinto, M. Sao-Jose Nascimento

Journal:

Year:

2009

File:

PDF, 27 KB

2009

4

ChemInform Abstract: Efficient Synthesis of 6-(Hetero)arylthieno[3,2-b]pyridines by Suzuki—Miyaura Coupling. Evaluation of Growth Inhibition on Human Tumor Cell Lines, SARs and Effects on the Cell Cycle.

Maria-Joao R. P. Queiroz, Ricardo C. Calhelha, Luis A. Vale-Silva, Eugenia Pinto, Raquel T. Lima, M. Helena Vasconcelos

Journal:

Year:

2011

Language:

english

File:

PDF, 32 KB

english, 2011

5

ChemInform Abstract: Synthesis and Evaluation of Tumor Cell Growth Inhibition of Methyl 3-Amino-6-[(hetero)arylethynyl]thieno[3,2-b]pyridine-2-carboxylates. Structure—Activity Relationships, Effects on the Cell Cycle and Apoptosis.

Maria-Joao R. P. Queiroz, Ricardo C. Calhelha, Luis A. Vale-Silva, Eugenia Pinto, Gabriela M. Almeida, M. Helena Vasconcelos

Journal:

Year:

2011

File:

PDF, 51 KB

2011

6

Antifungal activity of synthetic di(hetero)arylamines based on the benzo[b]thiophene moiety

Eugénia Pinto, Maria-João R.P. Queiroz, Luís A. Vale-Silva, João F. Oliveira, Agathe Begouin, Jeanne-Marie Begouin, Gilbert Kirsch

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 226 KB

english, 2008

7

Investigation of the mechanism of action of 3-(4-bromophenyl)-5-acyloxymethyl-2,5-dihydrofuran-2-one against Candida albicans by flow cytometry

Luís A. Vale-Silva, Vladimír Buchta, Doris Vokurková, Milan Pour

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

8

Synthesis of novel 3-(aryl)benzothieno[2,3-c]pyran-1-ones from Sonogashira products and intramolecular cyclization: Antitumoral activity evaluation

Maria-João R.P. Queiroz, Ricardo C. Calhelha, Luís A. Vale-Silva, Eugénia Pinto, M. São-José Nascimento

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 550 KB

english, 2009

9

Novel 6-[(hetero)arylamino]thieno[3,2-b]pyridines: Synthesis and antitumoral activities

Maria-João R.P. Queiroz, Ricardo C. Calhelha, Luís A. Vale-Silva, Eugénia Pinto, M. São-José Nascimento

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 734 KB

english, 2010

10

Synthesis and evaluation of tumor cell growth inhibition of methyl 3-amino-6-[(hetero)arylethynyl]thieno[3,2-b]pyridine-2-carboxylates. Structure–activity relationships, effects on the cell cycle and apoptosis

Maria-João R.P. Queiroz, Ricardo C. Calhelha, Luís A. Vale-Silva, Eugénia Pinto, Gabriela M. Almeida, M. Helena Vasconcelos

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 205 KB

english, 2011

11

Antifungal susceptibility testing by flow cytometry: is it the future?

Luís André Vale-Silva, Vladimír Buchta

Journal:

Year:

2006

Language:

english

File:

PDF, 196 KB

english, 2006

12

New potential antitumoral di(hetero)arylether derivatives in the thieno[3,2-b]pyridine series: Synthesis and fluorescence studies in solution and in nanoliposomes

Maria-João R.P. Queiroz, Sofia Dias, Daniela Peixoto, Ana Rita O. Rodrigues, Andreia D.S. Oliveira, Paulo J.G. Coutinho, Luís A. Vale-Silva, Eugénia Pinto, Elisabete M.S. Castanheira

Journal:

Journal of Photochemistry and Photobiology A: Chemistry

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

13

Nanoliposomes for encapsulation and delivery of the potential antitumoral methyl 6-methoxy-3-(4-methoxyphenyl)-1H-indole-2-carboxylate

Ana S Abreu, Elisabete MS Castanheira, Maria-João RP Queiroz, Paula MT Ferreira, Luís A Vale-Silva, Eugénia Pinto

Journal:

Nanoscale Research Letters

Year:

2011

Language:

english

File:

PDF, 217 KB

english, 2011

14

Interaction of antitumoral fluorescent heteroaromatic compounds, a benzothienopyrrole and two thienoindoles, with DNA and lipid membranes

Ana S. Abreu, Elisabete M.S. Castanheira, Paulo J.G. Coutinho, Maria-João R.P. Queiroz, Paula M.T. Ferreira, Luís A. Vale-Silva, Eugénia Pinto

Journal:

Journal of Photochemistry and Photobiology A: Chemistry

Year:

2012

Language:

english

File:

PDF, 1.08 MB

english, 2012

15

Aspergillus viridinutans : an agent of adult chronic invasive aspergillosis

Coelho, Danina, Silva, Susana, Vale-Silva, Luís, Gomes, Helena, Pinto, Eugénia, Sarmento, António, Pinheiro, Maria Dolores

Journal:

Medical Mycology

Year:

2011

Language:

english

File:

PDF, 339 KB

english, 2011

16

Antifungal activity of the essential oil of Thymus villosus subsp. lusitanicus against Candida, Cryptococcus, Aspergillus and dermatophyte species

Pinto, Eugénia, Gonçalves, Maria José, Hrimpeng, Karnjana, Pinto, Jéssica, Vaz, Sara, Vale-Silva, Luís André, Cavaleiro, Carlos, Salgueiro, Lígia

Journal:

Industrial Crops and Products

Year:

2013

Language:

english

File:

PDF, 737 KB

english, 2013

17

Lycopersicon esculentum Seeds: An Industrial Byproduct as an Antimicrobial Agent

Taveira, Marcos, Silva, Luís R., Vale-Silva, Luís A., Pinto, Eugénia, Valentão, Patrícia, Ferreres, Federico, Guedes de Pinho, Paula, Andrade, Paula B.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2010

Language:

english

File:

PDF, 830 KB

english, 2010

18

Targeted Metabolite Analysis and Biological Activity of Pieris brassicae Fed with Brassica rapa var. rapa

Pereira, David M., Noites, Alexandra, Valentão, Patricia, Ferreres, Federico, Pereira, José A., Vale-Silva, Luis, Pinto, Eugénia, Andrade, Paula B.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2009

Language:

english

File:

PDF, 822 KB

english, 2009

19

Antifungal Activity of the Essential Oil of Thymus x viciosoi against Candida, Cryptococcus, Aspergillus and Dermatophyte Species

Vale-Silva, Luís, Gonçalves, Maria, Cavaleiro, Carlos, Salgueiro, Lígia, Pinto, Eugénia

Journal:

Year:

2010

File:

PDF, 152 KB

2010

20

Antifungal Activity of the Essential Oil of Thymus x viciosoi against Candida, Cryptococcus, Aspergillus and Dermatophyte Species

Vale-Silva, Luís, Gonçalves, Maria, Cavaleiro, Carlos, Salgueiro, Lígia, Pinto, Eugénia

Journal:

Year:

2010

Language:

english

File:

PDF, 152 KB

english, 2010

21

Inhibiting fungal multidrug resistance by disrupting an activator–Mediator interaction

Nishikawa, Joy L., Boeszoermenyi, Andras, Vale-Silva, Luis A., Torelli, Riccardo, Posteraro, Brunella, Sohn, Yoo-Jin, Ji, Fei, Gelev, Vladimir, Sanglard, Dominique, Sanguinetti, Maurizio, Sadreyev, Ru

Journal:

Year:

2016

Language:

english

File:

PDF, 8.30 MB

english, 2016

22

Upregulation of the Adhesin Gene EPA1 Mediated by PDR1 in Candida glabrata Leads to Enhanced Host Colonization

Vale-Silva, Luis A., Moeckli, Beat, Torelli, Riccardo, Posteraro, Brunella, Sanguinetti, Maurizio, Sanglard, Dominique, Lorenz, Michael

Journal:

Year:

2016

Language:

english

File:

PDF, 1.73 MB

english, 2016

23

Aminodi(hetero)arylamines in the Thieno[3,2-b]pyridine Series: Synthesis, Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Evaluation of Toxicity Using Non-Tumor Cells

Calhelha, Ricardo C., Ferreira, Isabel C. F. R., Peixoto, Daniela, Abreu, Rui M. V., Vale-Silva, Luís A., Pinto, Eugénia, Lima, Raquel T., Alvelos, M. Inês, Vasconcelos, M. Helena, Queiroz, Maria-João

Journal:

Year:

2012

Language:

english

File:

PDF, 187 KB

english, 2012

24

Comparative Genomics of Two Sequential Candida glabrate Clinical Isolates

Vale-Silva, Luis, Beaudoing, Emmanuel, Tran, Van Du T., Sanglard, Dominique

Journal:

G3 Genes|Genome|Genetics

Year:

2017

Language:

english

File:

PDF, 984 KB

english, 2017

25

SNP-ChIP: a versatile and tag-free method to quantify changes in protein binding across the genome

Vale-Silva, Luis A., Markowitz, Tovah E., Hochwagen, Andreas

Journal:

Year:

2019

Language:

english

File:

PDF, 3.65 MB

english, 2019

26

Stem cell-derived polarized hepatocytes

Dao Thi, Viet Loan, Wu, Xianfang, Belote, Rachel L., Andreo, Ursula, Takacs, Constantin N., Fernandez, Joseph P., Vale-Silva, Luis Andre, Prallet, Sarah, Decker, Charlotte C., Fu, Rebecca M., Qu, Bing

Journal:

Nature Communications

Year:

2020

File:

PDF, 3.21 MB

2020

27

Topoisomerases Modulate the Timing of Meiotic DNA Breakage and Chromosome Morphogenesis in Saccharomyces cerevisiae

Heldrich, Jonna, Sun, Xiaoji, Vale-Silva, Luis A., Markowitz, Tovah E., Hochwagen, Andreas

Journal:

Year:

2020

File:

PDF, 2.26 MB

2020

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